SandMan™contains 250mg of glutathione, 200mg of Melatonin, Terpenes, Proprietary blend of SandMan Complex™ (CBD from whole plant hemp extract and magnolia) along with our proprietary AP0-808™ probiotic strain. The body’s most powerful anti-oxidant (Glutathione), is combined with the brains primary anti-oxidant (melatonin), along with SandMan Complex™ for neurotransmitter support for GABA to aid in deep relaxation. This is the most advanced and strongest sleep support, with a slow release over a 5-7 hour period, to support sleep all night long due to our proprietary slow release technology using SRT ™ Polysaccharide Complex. Deep sleep has been clinically shown to support the break down of amyloid beta protein tangles. Another important and recent finding in science of sleep, is that Deep sleep cleanses the brain. The waste removal system of the brain, the glymphatic system, is at its most efficient during deep sleep, a recent international study shows it may be possible that getting too little deep sleep prevents glymphatic clearance and can cause neurological diseases. Basically your neurons will be swimming in their own excrement without adequate deep sleep.
“I’m one of those guys who often takes oral supplements and notices next to nothing. That’s not uncommon. Digestion, pass through the liver, the acidic nature of the stomach and a host of other factors can keep you from properly absorbing precious molecules. But when I tried Dr. Lieurance’s nasal sprays and suppositories I noticed them almost immediately. I have now used them successfully for jet lag, inflammation and enhanced sleep and I’m completely enamored: these things are the real deal – and a valuable arsenal to any health hacker’s toolkit.”
Research on Melatonin
Research on Melatonin
Melatonin is 4x more potent, as a free radical scavenger, than antioxidants such as (vitamin C or E)! Plus for very molecule of melatonin 10 free radicals are scavenged. This is a massive antioxidant load that Melatonin takes on! Melatonin doesn’t stop there it also transforms free radicals to “melatonin metabolites” which also act as free radical scavengers. This process is referred to as “the free radical scavenging cascade”. No other known antioxidant is capable of exerting this remarkably double effect as an antioxidant! All other major antioxidants in the body, such as glutathione (GSH), superoxide dismutase (SOD), catalase (CAT) are activated by Melatonin! Sandman provides 200mg of absorbable Melatonin that is time released. Studies show oral Melatonin is only 2.5% absorbed! Sandman delivers unparalleled and essential brain and body protection and anti-aging effects.
“We explore the mechanism of melatonin that is associated with the role of stress as a key factor to precipitate depression and as a factor altering neurogenesis, supporting the notion that melatonin possesses anti-stress and neurogenic actions. On the other hand, melatonin shows a pleiotropic character and it is a versatile and ubiquitous antioxidant molecule with low toxicity and high efficacy in reducing oxidative damage. Furthermore, melatonin has anti-inflammatory effects by regulation of multiple cellular pathways and properties to prevent excitotoxicity, among others.” (Ref)
There has been over 4,000 publications in peer review journals in the National Library of Medicine confirming melatonin, in super high physiologic dosages is safe and not toxic with dosages as high as 52,000 mg in animal models showing no toxicity. It has been shown in these studies to be the most powerful antioxidant our bodies use!
This video by Dr Reiter is an excellent place to start with your own journey to discover melatonin and how it may help you.
Below is Dr Been’s Melatonin Presentation. Warning: Its a very deep dive!
Dosage and Storage Instructions: Wash your hands thoroughly with soap and water. Keep the suppository in the refrigerator so it remains hard before removing the wrapper. Put on a finger cot or disposable glove, if desired (available at a pharmacy). Lubricate the suppository with a water soluble lubricant such as K-Y Jelly or coconut oil, not petroleum jelly (Vaseline). If you do not have this lubricant, moisten your rectal area with cool tap water. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Lift upper buttock to expose the rectal area. Insert the suppository, pointed end first, with your finger until it passes the muscular sphincter of the rectum, about ½ to 1 inch in infants and 1 inch in adults (If not inserted past this sphincter, the suppository may pop out). Hold buttocks together for a few seconds. Remain lying down for about 5 minutes to avoid having the suppository come out. Discard used materials and wash your hands thoroughly.
Suggested dosage is 1 (one) suppository daily. Depending on your daily schedule, it is recommended that you insert the suppository prior to bed.
You might need to become accustomed to the high melatonin dosing so start with 1/2 and work up to it. If you feel groggy go get in the sunlight in the morning as melatonin plus light especially in the eyes you wont be tired.
Supplement Facts: Sandman
Serving size: 1 Servings: 15
Amount Per Piece % Daily Value
L Glutathione 250mg
Magnolia / Hemp Extract. **/20mg
AP0-808 Probiotic Blend *****
SRT Polysaccharide Complex. *****
Full Spectrum Hemp Extract 20mg
Terpene Profile: Linalool, Myrcene *****
Essential Oils: Boswellia, Copaiba *****
Organic Palm Oil. *****
Many folks are uneasy with even mentioning of rectal suppositories until they realize how very powerful this approach can prove to be. For some navigating around this phobia could make the difference between health and sickness or enhanced performance for those biohackers!
There is a growing acknowledgement of the need to provide safer, more cost-effective treatments that can either reduce the need for pharmaceuticals (ie: drugs) and/or to reduce their side effects. There is a mountain of research to demonstrate vitamins, extracts, nutrients, herbals and nutraceuticals can do just that, if only they could be absorbed in such a manner as to allow greater therapeutic effect. <h4>How do Rectal Suppositories Work?</h4> Everything, when administered orally, is absorbed from the gastrointestinal tract into the portal venous circulation and pass through the liver (first pass metabolism) where the process of metabolism or breakdown begins. Suppositories, like intravenous (IV), intramuscular (IM), and transdermal methods of administration, bypass this “first pass” effect and are absorbed into the rectal veins without encountering liver metabolism. Fortunately, the rectum is filled with blood vessels that offer direct access into the body’s bloodstream. This allows for rapid access to systemic circulation.
When nutrients are put into our special suppository base they are protected and delivered through Slow Release Technology along with the support of the probiotics APO-808. All Glutagenic’s™’s proprietary suppository base is formulated with ingredients that promote the movement of the active nutrients from the base to the rectum.This technology facilitates solubility, and allows a compound that is usually insoluble in water (hydrophobic) to dissolve, and thus be absorbed. This is crucial for poorly absorbed compounds.
<strong>GlutaGenic’s suppositories are easy to insert, non-irritating, rapid-melting, fully absorbed in 5-10 minutes, and you’ll not know its in there after insertion.</strong>
Terpenes: They are the fragrant essence of ALL essential oils! They give plants their unique smell and they also hold the healing benefits within the plants. Terpenes have been studied extensively and they are at the forefront of interest of the pharmaceutical companies due to the unique and safe profile they can have. Terpenes that are specifically shown to reduce pain, are anti inflammatory and reduce anxiety have been incorporated into Sandman™.* These terpenes also have been shown to improve CBD and other cannabinoids utilization and uptake into the brain.*
Myrcene (or β-myrcene)is a terpene that occurs often in highly fragrant plants and herbs such as mangoes, hops, bay laurel leaves, thyme, lemongrass, and basil. Myrcene is produced by numerous cannabis strains, and some rodent-model studieshave suggested that it might lend sedative effects. Main effects are Anti-inflammatory, Analgesic (pain relief), Antibiotic, Mood Elevation and Antimutagenic (anti cancer).*
Another place you’ll find myrcene is in mangoes. Anecdotal evidence suggests that eating a ripe mango prior to consuming cannabis may accentuate or extend the effects of cannabinoids; some have suggested that this is due to the fruit’s concentrations of myrcene, which is naturally synergistic with CBD and allows cannabinoids to more easily bridge the blood-brain barrier
Boswellia,or Indian frankincense, is a resin herbal extract from the boswellia tree, which natural medicine practices have used for centuries. Its anti-inflammatory effects mean that it may help with inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease, and asthma. We included this amazing extract into our products due to all of the positive healing properties
Linaloolis a naturally occurring terpene found in many flowers and spices including lavender and coriander. It gives off a complex yet delicate floral aroma, and while its effects are myriad, it is in particular one of the substances used most widely to reduce stress. Humans have inhaled the scent of certain plants, including many containing linalool, since ancient times to help lower stress levels, fight inflammation, and combat depression.* Linalool has been the subject of many studies, including a recent onein which scientists allowed lab rats to inhale linalool while exposing them to stressful conditions. It was reported that linalool returned elevated stress levels in the immune system to near-normal conditions. Linalool’s Effects and Benefits include anti-anxiety, Antidepressant, Mood Elevation, Anti-inflammatory, Anti-epileptic and Analgesic.*
Disclosures and Disclaimers
Disclosures and Disclaimers
DO NOT DRIVE OR OPERATE MACHINERY AFTER CONSUMING THIS PRODUCT
Store this product in a refrigerated climate. Keep this product away from sunlight. Please use the product within six months of purchase date for best results.
Glutagenic does not sell or distribute any products that are in violation of the United States Controlled Substances Act (USA CDA). The company does sell and distribute hemp-based products.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent disease or medical conditions. The products and information found on GlutaGenic.com are not intended to replace professional medical advice or treatment. Individual results may vary. GlutaGenic urges you to seek the advice of a qualified professional for any health concern, and to share with your provider any information pertaining to your health and well-being, including the use of supplemental nutrition. We try our best not to make mistakes; however, if typographical errors appear in our site, we cannot be held responsible. All information presented here is not meant as a substitute for or alternative to information from healthcare practitioners. Please consult your healthcare professional about potential interactions or other complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice.
Shipping & Delivery
During the hot summer months, we recommend taking advantage of the cold shipping option to ensure product stability upon arrival.
Orders placed on a Thursday or Friday and requiring cold shipping will not ship until the following Monday.
Orders placed over the weekend will not be shipped until Monday.
StemZen™- (Phase 3 Upgrade) 2 of the most powerful stem cell supporting nutrients, probiotics & SRT™ for sustained release. This product is designed to maximize stem cell survival. Evidence of both Fucoidan and CoQ-10 with the prevention of stem cell senescence is clear, which allows more stem cells to do the regenerative work for you. CoQ-10 has been shown to have poor absorption orally, so suppository route can allow much higher bioavailability of CoQ-10.
StemZen comes in a pack of 10 suppositories.
Take StemZen™ in Phase 3 to support stem cells that are released after you Fast.
Spore Based Probiotics & Butyrate in a Suppository? What a great idea!
Butyrate is a short-chain fatty acid essential for optimal digestive health. Holistic health care advocates have been using butyrate in the form of an enema for many years throughout the U.S. Now we are able to offer the same effective strategy in the form of a suppository. There is evidence in the literature that supplementing with butyrate can support people with distal ulcerative colitis and inflammatory bowel conditions like Crohn’s disease. The important function that butyrate serves in the digestive system is to reduce inflammation, however it has numerous other benefits. Butyrate is a byproduct of the digestive process that can strengthen colonic defenses, prevent re-uptake of toxins into the body, and increase intestinal barrier function. Since butyrate is found naturally in a healthy colon, suppository use can be a safe and effective route of delivery. When butyrate levels in the digestive system are low, it can result in ulcerative colitis, Crohn’s, and for some without an IBD condition it can cause diarrhea. A butyrate suppository is used to help restore the levels of butyrate in the colon. Our sodium butyrate suppositories are made of the highest quality materials.
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